Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| KTB13 | 97.KTB13 | DRC | 1997 | HIV1 | A | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| T97A | K14R, A21T, I72V, L101I, T112V, T124A, T125A, G134N, K136Q, L234I | S283G |
| >97.KTB13| codons 1-288 FLDGIDKAQEEHERYHSNWRTMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQEAAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWANIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, E35D, M36I, R41K, H69K, L89M |
| >97.KTB13| codons 1-99 PQITLWQRPIVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, K49R, V60I, K122E, D123G, T139A, K173A, Q174K, I178M, T200A, Q207D, R211K, V245Q, A272P, T286A, I293V, P294E, D324E, G335D, R356K, M357K, G359S, K366R, I375V, T377L, K390R, T403M, E404D, E432D, V435A, A437V, D471E, Q480H, H483Y, L491S, A502V, K512R, E516G, S519N, Q524K, K527E, A534S, A554S |
| >97.KTB13| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNEAPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPDMVI YQYMDDLYVGSDLEIGQHRAKIEELRDHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVVELTEEAE LELAENREILKEPVHGVYYDPSKELIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA HTNDVRQLTEAVQKVALESIVIWGKTPKFRLPIQKETWEAWWMDYWQATWIPEWEFVNTP PLVKLWYQLEKDPIAGVETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH AIYLALQDSGSEVNIVTDSQYVLGIIQAQPDRSESGLVNQIIEKLIEKEKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Vidal, N | Identification and molecular characterization of subsubtype A4 in central Africa. | ARHR, 2006 |