Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| KCC2 | 97.KCC2 | DRC | 1997 | HIV1 | A | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, A21T, I72V, L101I, T112V, T125A, G134S, K136Q, D167E, I208L, L234I | S283G |
| >97.KCC2| codons 1-288 FLDGIDKAQEEHERYHSNWRTMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSTAVKAACWWASIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIVDIIATDLQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13V, K14R, I15V, G16E, E35D, M36I, R41K, R57K, H69K, L89M |
| >97.KCC2| codons 1-99 PQITLWQRPVVTVRVEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| P4S, V35T, T39N, V60I, K64R, K122A, D123N, I135T, S163T, K173S, Q174K, D177E, T200A, Q207A, R211K, V245Q, A272P, K281R, L283I, T286A, E291D, V292I, I293V, P294T, R356K, M357K, G359S, K366R, T369S, A371V, I375V, K390R, T403M, E404D, E432D, D471E, Q480H, H483Y, L491S, K512I, L517I, S519N, Q524K, K527E, A534S, A554S |
| >97.KCC2| codons 1-560 PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNEMEKEGKISKIGPENPYNTPI FAIRKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DANFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSTMTKILEPFRSKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLIRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKKRSA HTNDVRQLSEVVQKVATESIVIWGKTPKFRLPIQKETWEAWWMDYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH AIYLALQDSGSEVNIVTDSQYALGIIQAQPDISESEIVNQIIEKLIEKEKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Vidal, N | Identification and molecular characterization of subsubtype A4 in central Africa. | ARHR, 2006 |