<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL227 06_PL227EN South Africa 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 None NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K32KE, V35T, T39E, S48T, V118I, K122E, D123N, I135R, T139A, K166KR, K173T, Q174R, T200A, Q207E, R211RK, F214L, A272S, K277R, T286A, E291D, V292I, I293V  
>06_PL227EN| codons 1-299
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIEALTEICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DENFRKYTAFTIPSRNNEAPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRTRNPDIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGAKALTDIVPLTEEA

References
Author Title Citation
Seoighe, C A model of directional selection applied to the evolution of drug resistance in HIV-1. Mol Bio Evol, 2007