Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| B-0402 | B-0402 | Spain | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | NA |
| 2 | 3TC+AZT | NA |
| 3 | 3TC+AZT+SQV | NA |
| 4 | 3TC+D4T+IDV | NA |
| 5 | 3TC+D4T+EFV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | I15V, G16E, E35D, M36I, P39S, I64V |
| >B-0402| codons 1-99 PQITLWQRPLVTIKVEGQLKEALLDTGADNTVLEDINLSGRWKPKMIGGIGGFIKVRQYD QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | K219E | K103N | V108VI | V118VI, I135T, D177E, I195L, T200AV, R211K, F214L, V245T, A272G, K277R, R284K, I293V, E297K |
| >B-0402| codons 1-320 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSIPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI YQYVDDLYVGSDLELGQHRVKIEELRQHLLKWGLTTPDEKHQKEPPFLWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYGGIKVRQLCKLLKGTKALTEVVPLTKEAE LELAENREILKEPVHGVYYD |
References
| Author | Title | Citation |
| Ochoa de Echaguen, A | Genotypic and phenotypic resistance patterns at virological failure in a simplification trial with nevirapine, efavirenz or abacavir. | AIDS, 2005 |