<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Pt15 FDB_Pt15 Botswana 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI+NVP 65

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R   K103KN, V106VM, Y181C   V35T, T39E, S48T, K122E, K173A, D177G, T200A, Q207E, R211K, V245Q, E248D, A272S, T286A, E291D, V292I A114AS, N136NST
>FDB_Pt15| codons 1-321
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV
FAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSMTVLDVGDSYFSVPL
DEDFRKYTAFTIPSITNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPGIVI
CQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGAKALTDIIPLTEEAE
LELAENREILKEPVHGVYYDP

References
Author Title Citation
Doualla-Bell, F High prevalence of the K65R mutation in human immunodeficiency virus type 1 subtype C isolates from infected patients in Botswana treated with didanosine-based regimens. AAC, 2006