<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Pt7 FDB_Pt7 Botswana 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI+NVP 17

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R   K103KN, Y181C, G190GA Y318F K22KN, V35T, T39K, S48E, T69N, D123DE, I135IM, K173IT, T200A, Q207E, R211K, V245Q, K277KR, K281KR, T286A, E291D, V292I, I293V E312F, V314P, Y319C
>FDB_Pt7| codons 1-321
PISPIETVPVKLKPGMDGPKVNQWPLTEEKIKALTEICKEMEKEGKIEKIGPENPYNTPV
FAIKRKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPDIVI
CQYMDDLYVASDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCRLLRGAKALTDIVPLTEEAE
LELAENREILKFPPHGVFCDP

References
Author Title Citation
Doualla-Bell, F High prevalence of the K65R mutation in human immunodeficiency virus type 1 subtype C isolates from infected patients in Botswana treated with didanosine-based regimens. AAC, 2006