Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt7 | FDB_Pt7 | Botswana | 2005 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+NVP | 17 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R | K103KN, Y181C, G190GA | Y318F | K22KN, V35T, T39K, S48E, T69N, D123DE, I135IM, K173IT, T200A, Q207E, R211K, V245Q, K277KR, K281KR, T286A, E291D, V292I, I293V | E312F, V314P, Y319C |
| >FDB_Pt7| codons 1-321 PISPIETVPVKLKPGMDGPKVNQWPLTEEKIKALTEICKEMEKEGKIEKIGPENPYNTPV FAIKRKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPDIVI CQYMDDLYVASDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCRLLRGAKALTDIVPLTEEAE LELAENREILKFPPHGVFCDP |
References
| Author | Title | Citation |
| Doualla-Bell, F | High prevalence of the K65R mutation in human immunodeficiency virus type 1 subtype C isolates from infected patients in Botswana treated with didanosine-based regimens. | AAC, 2006 |