<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Pt10 FDB_Pt10 Botswana 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI+NVP 17

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R D67DG Y181C   T39E, E40K, E79ED, D86DG, K102KQ, K122E, K173A, T200A, Q207E, R211K, H221Y, L228LR, V245E, D250E, A272P, K277R, E291D, V292I, I293V T139TP, D177GR
>FDB_Pt10| codons 1-321
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICEKMEKEGKISKIGPENPYNTPV
FAIKRKGSTKWRKLVDFRDLNKRTQGFWEVQLGIPHPAGLKQKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNEPPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPRIVI
CQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKYQKEPPFRWMGYELHPDKWT
VQPIELPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDP

References
Author Title Citation
Doualla-Bell, F High prevalence of the K65R mutation in human immunodeficiency virus type 1 subtype C isolates from infected patients in Botswana treated with didanosine-based regimens. AAC, 2006