<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Pt13 FDB_Pt13 Botswana 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI+EFV 65
2 3TC+AZT+NFV 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, K70R, Y115F, Q151M V75A, F77L, F116Y, K219E K103N, V106M P225H V35T, E36A, T39E, T58N, S68G, K122E, D123S, R172K, K173T, D177E, I178M, T200A, Q207K, R211K, V245Q, E248D, A272P, K277R, E291D, V292I  
>FDB_Pt13| codons 1-321
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKISKIGPENPYNNPV
FAIKRKDGTRWRKLADLRELNKRTQDFWEVQLGIPHPAGLKKNKSMTVLDVGDAFYSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFKTQNPEMVI
YQYMDDLYVGSDLEIGQHRAKIEELRKHLLKWGFTTPDEKHQKEHPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIIPLTEEAE
LELAENREILKEPVHGVYYDP

References
Author Title Citation
Doualla-Bell, F High prevalence of the K65R mutation in human immunodeficiency virus type 1 subtype C isolates from infected patients in Botswana treated with didanosine-based regimens. AAC, 2006