Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt23 | FDB_Pt23 | Botswana | 2005 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NVP | 43 |
| 2 | 3TC+D4T+NVP | 9 |
| 3 | AZT+DDI+NFV | 52 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, V75T, T215Y | Y181C | V108I, V179D | K20R, V35T, T39D, E44D, D121C, K122E, I135T, E138A, K173T, D177E, I178L, V189I, T200A, E203D, E204K, Q207D, R211K, H221Y, P243S, V245Q, A272P, E291D, V292I, I293V |
| >FDB_Pt23| codons 1-321 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICDELEKDGKISKIGPENPYNTPV FAIKKKNSDKWRKLTDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYFSVPL CEDFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPELDI CQYMDDLYIGSDLEIGQHRAKIDKLRDHLLKWGFYTPDKKYQKEPPFLWMGYELHPDKWT VQSIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDP |
References
| Author | Title | Citation |
| Doualla-Bell, F | High prevalence of the K65R mutation in human immunodeficiency virus type 1 subtype C isolates from infected patients in Botswana treated with didanosine-based regimens. | AAC, 2006 |