<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Pt23 FDB_Pt23 Botswana 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+NVP 43
2 3TC+D4T+NVP 9
3 AZT+DDI+NFV 52

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, T215Y V75T Y181C V108I, V179D K20R, V35T, T39D, E44D, D121C, K122E, I135T, E138A, K173T, D177E, I178L, V189I, T200A, E203D, E204K, Q207D, R211K, H221Y, P243S, V245Q, A272P, E291D, V292I, I293V  
>FDB_Pt23| codons 1-321
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICDELEKDGKISKIGPENPYNTPV
FAIKKKNSDKWRKLTDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYFSVPL
CEDFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPELDI
CQYMDDLYIGSDLEIGQHRAKIDKLRDHLLKWGFYTPDKKYQKEPPFLWMGYELHPDKWT
VQSIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDP

References
Author Title Citation
Doualla-Bell, F High prevalence of the K65R mutation in human immunodeficiency virus type 1 subtype C isolates from infected patients in Botswana treated with didanosine-based regimens. AAC, 2006