<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
260Pt14 260Pt14W8C U.S. 1996 HIV1 B PBMC None

Treatment History
Order Regimen Weeks
1 AZT NA
2 DLV 8

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R K219Q Y181C   K103R, Q174X, G196E, Q207R, F214L  
>260Pt14W8C| codons 26-245
LTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQ
DFWEVQLGIPHPAGLKKRKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQ
YNVLPQGWKGSPAIFQSSMTKILEPFRKXNPDIVICQYMDDLYVGSDLEIEQHRTKIEEL
RRHLLRWGLTTPDQKHQKEPPFLWMGYELHPDKWTVQPIV

References
Author Title Citation
Demeter, LM Delavirdine susceptibilities and associated reverse transcriptase mutations in human immunodeficiency virus type I isolates from patients in a phase I/II trial of delavirdine monotherapy (ACTG 260). AAC, 2000
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005