Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL0754 | PL0754 | Nigeria | 2001 | HIV1 | CRF02_AG | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, G16E, K20I, E35K, M36I, N37E, R41K, H69K, L89M |
| >PL0754| codons 1-99 PQITLWQRPLVTVKIEGQLIEALLDTGADDTVLEKIELPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35K, E36D, D123E, I135T, S162A, K173T, Q174E, D177G, V189I, T200A, I202V, Q207K, V245Q, D250E, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, T369A, E370A, K374R, I375V, A376S, K385R, K390R, K395R, T403M, V417I, E432D, D471E, Q480H, H483Y, L491S, K512R, S519N, Q524K, K527G, E529D, A534S, A554N, K558R, V559I |
| >PL0754| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALKDICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTENPGIVI YQYMDDLYIGSDLEIGQHRAKVEELRKHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA HTNDVKQLAAAVQRVSTESIVIWGRTPKFRLPIQRETWEAWWMEYWQATWIPEWEFINTP PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH AIYLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEKLIGKDKVYLSWVPAHK GIGGNEQVDKLVSNGIRRIL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, D253H, D256E, A265V, R269K | S283G |
| >PL0754| codons 1-288 FLDGIDKAQEEHERYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWANVTQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQHNSEIKVVPRRKVKIIKDYGKQMAGDDCVAGRQDED |
References
| Author | Title | Citation |
| Carr, JK | HIV subtype and drug resistance patterns among drug-naive infected persons in Jos, Nigeria. | Direct Genbank Submission, 2005 |