<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL0710 PL0710 Nigeria 2001 HIV1 CRF02_AG PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12A, I13V, K14R, G16E, K20I, E35D, M36I, R41K, L63A, H69K, L89M  
>PL0710| codons 1-99
PQITLWQRPLVAVRIEGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIAIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V21I, V35T, T39M, I135V, S162A, K173T, Q174S, D177E, T200A, Q207G, R211K, V245K, D250E, S251D, K275R, V276I, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, A376T, T377V, K390R, A400T, T403V, E432D, V435P, A437I, S468T, D471E, Q480H, L491S, E492Q, K512R, L517I, S519N, Q524K, K527E, E529D, A534S, A554N, I556V  
>PL0710| codons 1-560
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICMEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTSNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKEDWTVNDIQKLVGKLNWASQIYAGIRIKQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPTKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA
HTNDVKQLTEVVQKVTVESIVIWGKTPKFRLPIQKETWETWWVEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIPGIETFYVDGAANRETKLGKAGYVTDRGRQKVVTLTETTNQKTELH
AIHLALQDSGSQVNIVTDSQYALGIIQAQPDRSESEIVNQIIEKLIEKDKVYLSWVPAHK
GIGGNEQVDKLVSNGVRKVL

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, K14R, V31I, K34R, M50I, S57G, A91S, L101I, K111R, T112V, T124A, T125A, G134N, K136T, V201I, T206S, L234I, D256E S283G
>PL0710| codons 1-288
FLDGIDKAQEDHERYHSNWRAMASDFNLPPIVAREIVASCDKCQLKGEAIHGQVDCGPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPSETGQETAYFILKLAGRWPVRVIHTDNGSN
FTSAAVKAACWWANITQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

References
Author Title Citation
Carr, JK HIV subtype and drug resistance patterns among drug-naive infected persons in Jos, Nigeria. Direct Genbank Submission, 2005