<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL0209P PL0209P Nigeria 2001 HIV1 G PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10M, I13V, K14R, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, L89M  
>PL0209P| codons 1-99
PQITLWQRPMVTVRIGGQLIEALLDTGADDTVLEQINLPGKWKPKMIGGIGGFIKVKQYD
QILIEIEGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, V60I, D121H, K122E, I135V, I142IV, K173L, Q174KR, D177E, I178L, T200A, Q207D, V245Q, D250E, S251D, K277R, T286A, E291D, V292I, I293V, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A376S, T377M, T386V, Q394K, A400I, E413D, K431T, V435L, F440Y, V458I, R461K, R463K, V467I, S468T, L469I, T470Q, D471E, Q480H, H483IL, Q487K, L491S, K512R, S519N, E529D, V531I, A534T, A554N Q258QR
>PL0209P| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
HEDFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRLRNPELVI
YQYMDDLYVGSDLEIGQHRAKIEELRDHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKEDWTVNDIRKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQGLDQWTYQIYQEPYKNLKTGKYAKRGSA
HTNDVKQLTEAVQKISMESIVIWGKVPKFKLPIKKETWEIWWTEYWQATWIPDWEFVNTP
PLVKLWYQLETEPILGAETYYVDGAANRETKLGKAGYITDKGKQKVITIQETTNQKTELH
AILLALKDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEQLIKKDKIYLTWVPAHK
GIGGNEQVDKLVSNGIRKVL

References
Author Title Citation
Carr, JK HIV subtype and drug resistance patterns among drug-naive infected persons in Jos, Nigeria. Direct Genbank Submission, 2005