Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1317 | CA7990 | U.S. | 1998 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | NA |
| 2 | 3TC+ AZT+ DDI | NA |
| 3 | None | 3 |
| 4 | D4T+ DDI+ IDV | 36 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y115F, Q151M | V75I, F77L, F116Y | K49R, I50V, S68G, K122E, T200A, E203EQ, Q207E, R211K, K219T, V245T, E248D, D250E, S251X, A272P, K277R |
| >CA7990| codons 1-284 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISRVGPENPYNTPV FAIKKKDGTKWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAFYSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRAKIQELREHLLKWGFTTPDTKHQKEPPFLWMGYELHPDKWT VQPITLPDKEXWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLR |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N88S | I15V, K20T, E35D, M36I, R57K, L63P, I93IL |
| >CA7991| codons 1-99 PQITLWQRPLVTIKVGGQLTEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVKQYD QIPIEICGHKAIGTVLVGPTPVNIIGRSLLTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |