<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
260Pt6 260Pt6W8C U.S. 1996 HIV1 B PBMC None

Treatment History
Order Regimen Weeks
1 AZT NA
2 DLV 8

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T215CY   K103N, Y181C   S68G, R83K, T139M, S162C, T200TI  
>260Pt6W8C| codons 30-244
KIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDGTKWRKLVDFRELNKKTQDFWE
VQLGIPHPAGLKKNKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNEMPGIRYQYNVL
PQGWKGSPAIFQCSMTKILEPFRKQNPDIVICQYMDDLYVGSDLEIGQHRIKIEELRQHL
LRWGFYTPDKKHQKEPPFLWMGYELHPDKWTVQPI

References
Author Title Citation
Demeter, LM Delavirdine susceptibilities and associated reverse transcriptase mutations in human immunodeficiency virus type I isolates from patients in a phase I/II trial of delavirdine monotherapy (ACTG 260). AAC, 2000
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005