Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA25602 | CA79443 | U.S. | 2007 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 52 |
| 2 | 3TC+ATV+EFV+RTV+TDF | 39 |
| 3 | 3TC+ATV+RTV+TDF | 52 |
| 4 | ATV+FTC+RTV+TDF | 16 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | F53L, G73S | K20V, L63P, A71V, V77I, I85IV |
| >CA79443| codons 1-99 PQITLWQRPLVTIKIGGQLVEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGLIKVRQYD QIPIEICGHKVISTVLIGPTPVNIVGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L210W, T215Y | D67G, K219R | K101E | K20R, K43N, E44D, K64H, V118I, D123E, E138A, I178M, R211K, D218E |
| >CA79444| codons 1-240 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELENDGKISKIGPENPYNTPV FAIHKKGSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSIPL DKEFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTPERKHQKEPPFLWMGYELHPDKWT |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease mutations and protease inhibitor cross resistance. | AAC, 2010 |