Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7885 | CA79323 | U.S. | 2006 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 44 |
| 2 | 3TC+AZT | 26 |
| 3 | D4T+IDV | 48 |
| 4 | 3TC+D4T+IDV | 213 |
| 5 | 3TC+APV+DLV+TDF | 57 |
| 6 | 3TC+APV+TDF | 52 |
| 7 | 3TC+APV+ATV+RTV+TDF | 61 |
| 8 | 3TC+ATV+FPV+RTV+TDF | 107 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32VI, M46L, I54L, V82VA, I84V, L90M | L10I, T12P, I15V, K20R, M36I, N37D, L63P, A71V, T74TS, P79S, I85V, I93L |
| >CA79323| codons 1-99 PQITLWQRPIVPIKVGGQLREALLDTGADDTILEEIDLPGRWKPKLIGGIGGFLKVRQYD QIPIEICGHKVIGSVLVGSTPANVVGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, M184V, L210W, T215Y | V75L, K219E | K103N | T39A, K122E, I135T, I178IM, I195IL, G196E, T200TA, L228N, E248N, D250E, T286A, A288S, I293V |
| >CA79324| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLLDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMVI YQYVDDLYVGSDLELEQHRAKIEELRQHLWRWGFYTPDEKHQKEPPFNWMGYELHPDKWT VQPIVLPNKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKSLTEVVPLTEEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease mutations and protease inhibitor cross resistance. | AAC, 2010 |