<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-8022 8022-30813 U.K. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184I, L210W, T215Y A62V K103N V108I P4S, E6D, E53D, W88C, V90I, D123E, T139K, S162A, F171Y, I178L, T200K, I202V, R211K, T240K, A272P, K281R, L283I, T286P, I293V, E297K, H315HY, R356K, G359S, A371V  
>8022-30813| codons 1-399
PISSIDTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPDNPYNTPV
FVIKKKDSTKWRKLVDFRELNKRTQDFCEIQLGIPHPAGLKKNKSVTILDVGDAYFSVPL
DKEFRKYTAFTIPSINNEKPGIRYQYNVLPQGWKGSPAIFQASMTKILEPYRKQNPDLVI
YQYIDDLYVGSDLEIGQHRKKVEELRQHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWK
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLIRGPKALTEVVPLTKEAE
LELAENREILKEPVYGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKMRSA
HTNDVKQLTEVVQKIATESIVIWGKTPKFKLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48V, I54V, V82A K43T E35D, M36I, R41K, I62V, L63P  
>8022-30813| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDINLPGKWTPKMIVGIGGFVKVRQYD
QVPIEICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006