Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-7227 | 7227-30828 | Spain | 2003 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74IV, M184V, L210W, T215Y | Y188L | V35K, T39E, K43R, E44D, S68G, D121H, K122E, I135T, S162C, R172K, K173S, D177E, I178L, T200A, E203K, Q207A, R211K, K223E, L228H, V245E, K277R, T286A, E291D, V292I, I293V, P294T, E297K, A304E, G335D, R356K, M357R, G359S, A360AT, T377V, T386I, K390R |
| >7227-30828| codons 1-399 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALKEICEELERDGKISKIGPENPYNTPV FAIKKKDGTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFKSQNPELVI YQYVDDLLVGSDLEIGQHRAKIKELRAHLWKWGFYTPDKKHQEEPPFHWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVTLTKEAE LELEENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKRRST HTNDVKQLTEAVQKIAVESIVIWGKIPKFRLPIQKETWE |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |