Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-7210 | 7210-30923 | Spain | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69T_VT, M184MI, L210W, T215Y | Y188L | V35T, K64R, K122E, D123DN, I135V, V179I, Q197E, T200A, Q207ST, R211K, V245M, I293V, E297K, Q334D, A360T, A376T, T386A, E399ED |
| >7210-30923| codons 1-399 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKEGKISKIGPENPYNTPV FAIRKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII YQYIDDLLVGSDLEIGEHRAKIEELRTHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTKEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGDGQWTYQIYQEPFKNLKTGKYARMRGT HTNDVKQLTEAVQKITTESIVIWGKAPKFKLPIQKETWD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54A, V82A, L90M | L33I | L10I, K20R, E35D, M36I, N37E, R57RK, I62IV, L63P, A71V, I93L |
| >7210-30923| codons 1-99 PQITLWQRPIVTIKIGGQLREALLDTGADDTVIEDIELPGRWKPKIIGGIGGFAKVKQYD QVPIEICGHKVIGTVLVGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |