<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-7209 7209-30923 Spain 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74LV, L210W, T215Y K219N L100I, K103N, Y181C   K43E, E44A, V118I, K122E, I135T, K166R, G196E, R211K, K223Q, L228H, Q242H, V245E, K277R, T286A, A288S, E297R, L301I, F346Y, R356K, M357R, A360I, A376S, K395R  
>7209-30923| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEAGKISKIGPENPYNTPV
FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIVI
CQYMDDLYVGSDLEIEQHRTKIEELRQHLWKWGFYTPDNKHQQEPPFHWMGYELHPDKWT
VHPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKSLTEVIPLTREAE
IELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPYKNLKTGKYAKRRGI
HTNDVKQLTEAVQKISTESIVIWGKTPKFKLPIQRETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54L, V82A, L90M L33F, G73S L10I, I13V, K20R, E35D, M36I, N37D, R41K, I62V, L63P, A71V, I72L  
>7209-30923| codons 1-99
PQITLWQRPIVTVKIGGQLREALLDTGADDTVFEDIDLPGKWKPKMIGGIGGFLKVRQYD
QVPIEICGHKVLSTVLVGPTPANIIGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006