Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9044 | 9044-30925 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54IV, V82F, I84V | L33F, T74P | L10I, I15V, G16E, Q18R, L19P, K20L, N37S, I62IV, V77VI, I85V, L89M |
| >9044-30925| codons 4-99 TLWQRPIVTIKVEGRPLEALLDTGADDTVFEEMSLPGRWKPKIIGGIGGFVKVRQYDQVL IEICGHKAIGPVLIGPTPFNVVGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, V75M, L210W, T215Y | K219N | G190E | K43N, E44AD, K101KQR, V118I, K122E, I135T, E138A, K166R, V179G, L187LS, I202V, R211K |
| >9044-30925| codons 38-247 CTELENDGKISKIGPENPYNTPVFAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIPHP AGLRKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSP AIFQSSMTRILEPFRKQNPDIGIYQYMDDSYVESDLEIGQHRTKVEELRQHLWKWGFYTP DNKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |