Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9139 | 9139-30925 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74I, V75T, M184V, L210W, T215Y | K219E | K103N | A98G | E44D, I94L, V118I, I135L, S162SN, T200A, E203D, H208HY, R211K, D218E |
| >9139-30925| codons 38-247 CTELEKDGKISKIGPENPYNTPVFAIKKKNSTRWRKITDFRELNKRTQDFWEVQLGLPHP GGLKKNKSVTVLDVGDAYFSIPLDKDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSP AIFQNSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRAKIDELRQYLWKWGFYTP EEKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, G48A, I54V, V82S | L10V, G16A, K20R, E35D, M36I, I62V, L63C, A71V, T74S, I93L |
| >9139-30925| codons 4-99 TLWQRPVVTIKIAGQLREALLDTGADDTVLEDINLPGRWKPKLIAGIGGFVKVRQYDQVC IEICGHKVIGSVLVGPTPSNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |