Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9125 | 9125-30918 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54A, V82C, I84V | L24I, L33F, K43T | L10I, L19I, K20R, E34EQ, E35D, M36I, N37S, I62V, L63P, I64V, A71V, Q92K |
| >9125-30918| codons 4-99 TLWQRPIVTIKIGGQIREALIDTGADDTVFQDISLPGRWTPKLIGGIGGFAKVRQYDQVP VEICGHKVIGTVLVGPTPCNVIGRNLLTKIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, L210W, T215Y | K219N | L100I, K103N, Y181C | A98G | E44D, V60I, V118I, K122E, I135T, I202V, E203A, Q207N, H208Y, R211K, K223Q, L228H |
| >9125-30918| codons 38-247 CTELEKDGKISKIGPENPYNTPIFAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP GGIKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVICQYMDDLYVGSDLEIGQHRTKVAELRNYLWKWGFYTP DNKHQQEPPFHWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |