Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9129 | 9129-30918 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | Y188L | T39A, E44ED, V118VI, K122E, D123E, T200TA, H208HY |
| >9129-30918| codons 38-247 CAELEKDGKISKIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSIPLDEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYMDDLLVGSDLEIGQHRAKIEELRQYLWRWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A, L90M | K43KT | L10IV, L19I, K20R, E35D, M36I, R41K, K55KR, R57K, D60E, Q61N, I62V, L63P, E65D, I72V, L89M | R8RG |
| >9129-30918| codons 4-99 TLWQGPVVTIKIGGQIREALLDTGADDTVLEDINLPGKWTPKLIGGIGGFVRVKQYENVP IDICGHKAVGTVLVGPTPANIIGRNMMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |