Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9133 | 9133-30918 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, M184V, L210W, T215CDGY | K219R | Y181C, G190A | V108I | K101Q, V111I, V118I, D121H, K122E, I135T, K166KR, V189VI, H208Y, R211K, H221Y |
| >9133-30918| codons 38-246 CTELEKEGKISKIGPENPYNTPVFAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP AGLQKKKSVTILDIGDAYFSIPLHEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTRILEPFRKQNPDIVICQYVDDLYIASDLEIGQHRTKIEELRQYLWKWGFYTP DRKYQKEPPFLWMGYELHPDKWTVQPIVL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54M, V82A, L90M | L33F, K43KT, Q58QE | L10I, R41K, D60E, I62V, L63P, A71V |
| >9133-30918| codons 4-99 TLWQRPIVTIKIGGQLKEALLDTGADDTVFEEMNLPGKWTPKLIGGIGGFMKVREYEQVP IEICGHKVIGTVLVGPTPANIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |