<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9135 9135-30918 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, D67N, V75M, Y115F, Q151M, T215Y F77L, F116Y     T39A, E53D, K101Q, K122E, D123N, I135IT, S162Y, I167V, I178L, H208Y, R211K, V245E V111VIM
>9135-30918| codons 38-247
CAELEKEGKISKIGPDNPYNTPVFAIKKKNSTKWRKLMDLRELNKRTQDFWEVQLGIPHP
AGLQKKKSVTVLDMGDAFYSVPLDENFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSP
AIFQYSMTKVLEPFRKQNPDLVIYQYMDDLYVGSDLEIGQHRTKIEELRQYLLKWGFYTP
DKKHQKEPPFLWMGYELHPDKWTVQPIELP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46FL, I54V, V82A L24I, L33F, K43T, G73S L10I, T12K, I15V, G16D, L19IM, K20M, E35DN, M36I, P39PS, K55R, I62V, L63P, A71V  
>9135-30918| codons 4-99
TLWQRPIVKIKVDGQMMEALIDTGADDTVFENINLSGRWTPKLIGGIGGFVRVRQYDQVP
IEICGHKVISTVLVGPTPANIIGRNLLTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006