<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9144 9144-30909 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70R, T215F D67ST, Q151QL, K219E K101E, Y181C, G190A A98AG, V108I, F227L T69N, V90I, K103R, K122E, R172K, D177E, G196E, T200A, E203K, K223E, L228R  
>9144-30909| codons 38-247
CTEMEKEGKISKIGPENPYNTPVFAIKKKTSNRWRKLVDFRELNKRTQDFWEIQLGIPHP
GGLEKRKSVTILDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPLGWKGSP
AIFQSSMTKILEPFKKQNPEIVICQYMDDLYVASDLEIEQHRAKIKELRQHLLRWGFFTP
DEKHQEEPPLRWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, I47V, I54M, L90M L10FI, G73GS, V82VG T12S, K14R, I15V, K20R, E35D, M36I, N37S, R41K, L63P, A71V, I85V L24LV, D29DV
>9144-30909| codons 4-99
TLWQRPIVSIRVGGQLREALVDTGAVDTILEDISLPGKWKPKMVGGIGGFMKVRQYDQIP
IEICGHKVISTVLVGPTPGNIVGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006