Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9150 | 9150-30908 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I54A, V82T, L90M | L10I, T12TS, L19I, K20M, M36MIV, I62V, L63P, I64V, A71V, I72V, I93L |
| >9150-30908| codons 4-99 TLWQRPIVSIKIGGQIMEALLDTGADDTVLEEVNLPGRWKPKMIVGIGGFAKVRQYDQVP VEICGHKVVGTVLVGPTPTNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215F | K219Q | K49R, K101KI, K122E, D123N, I135T, T139M, D177E, V179I, I202V, R211K, L228LH | E53EK |
| >9150-30908| codons 38-247 CTEMEKEGKISRIGPKNPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLIKKKSVTVLDVGDAYFSVPLDENFRKYTAFTIPSTNNEMPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPEIIIYQYVDDLYVGSDLEIGQHRTKVEELRQHLLKWGFFTP DQKHQKEPPFHWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |