Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9151 | 9151-30826 | Brazil | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74LI, M184V, L210W, T215Y | K101KE, Y181C, G190GA | V108I | E44D, K49R, V118I, K122E, I135V, S162C, E169A, K173A, Q174K, E203K, Q207E, R211K, H221Y, L228R, V245P |
| >9151-30826| codons 38-247 CTELEKDGKISRIGPENPYNTPVFAIKKKDSTKWRKIVDFRELNKRTQDFWEVQLGIPHP AGLEKKKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILAPFRAKNPDIVICQYVDDLYVASDLEIGQHRTKIKELREHLWKWGFYTP DKKYQKEPPFRWMGYELHPDKWTVQPIPLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46FL, I54V, V82A, L90M | L10I, K20R, E35D, M36I, N37DE, R41K, K55R, R57K, D60E, Q61N, L63P, H69Y, A71V, I72T, V77I, L89M, I93L |
| >9151-30826| codons 4-99 TLWQRPIVTIKIGGQLREALLDTGADDTVLEDIELPGKWKPKLIGGIGGFVRVKQYENIP IEICGYKVTGTVLIGPTPANIIGRNMMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |