<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9151 9151-30826 Brazil 2003 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46FL, I54V, V82A, L90M   L10I, K20R, E35D, M36I, N37DE, R41K, K55R, R57K, D60E, Q61N, L63P, H69Y, A71V, I72T, V77I, L89M, I93L  
>9151-30826| codons 4-99
TLWQRPIVTIKIGGQLREALLDTGADDTVLEDIELPGKWKPKLIGGIGGFVRVKQYENIP
IEICGYKVTGTVLIGPTPANIIGRNMMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74LI, M184V, L210W, T215Y   K101KE, Y181C, G190GA V108I E44D, K49R, V118I, K122E, I135V, S162C, E169A, K173A, Q174K, E203K, Q207E, R211K, H221Y, L228R, V245P  
>9151-30826| codons 38-247
CTELEKDGKISRIGPENPYNTPVFAIKKKDSTKWRKIVDFRELNKRTQDFWEVQLGIPHP
AGLEKKKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP
AIFQCSMTKILAPFRAKNPDIVICQYVDDLYVASDLEIGQHRTKIKELREHLWKWGFYTP
DKKYQKEPPFRWMGYELHPDKWTVQPIPLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006