<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9121 9121-30930 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, L74I, L210W, T215Y V75T, K219E Y181C, G190A K101HN, V108I E40F, K43E, V106VI, L109LV, V118I, D123E, D177E, V189VI, Q197E, T200TI, D218E, L228H, I244M, V245M D76DN, S162ADHP, H235HR
>9121-30930| codons 38-247
CTFLEEEGKISKIGPENPYNTPVFAIKKKNSTRWRKITNFRELNKRTQDFWEVQLGIPHP
AGLNKKKSITIVDVGDAYFSIPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQPSMTKILEPFRKQNPEIVICQYMDDLYIASDLEIGEHRIKIEELRQHLWRWGFYTP
EEKHQKEPPFHWMGYELRPDKWTVQPMMLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, I84V, L90M L10F, L33F, Q58E, G73T V11G, E34Q, I62V, L63P, I66V, C67F, H69Q, I72LV, V77VI, I93L  
>9121-30930| codons 4-99
TLWQRPFGTIKIGGQLKEALLDTGADDTVFQEMNLPGRWKPKIIGGIGGFVKVREYDQVP
IEVFGQKAVTTVLIGPTPVNVIGRNLMTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006