Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9123 | 9123-30930 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215F | K219E | K103N | V60I, T69N, K122E, I135T, S162A, Q174H, V179I, V245E | L228Y |
| >9123-30930| codons 38-247 CTEMEKEGKISKIGPENPYNTPIFAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQASMTKILEPFRKHNPDIIIYQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFFTP DEKHQKEPPFYWMGYELHPDKWTVQPIELP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | G73T | L10I, K20I, N37E, I62V, L63P, C67F, K70R, V77VI |
| >9123-30930| codons 4-99 TLWQRPIVTIKIGGQLIEALLDTGADDTVLEEMELPGRWKPKIIGGIGGFVKVRQYDQVP IEIFGHRAITTVLIGPTPVNVIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |