Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9115 | 9115-30924 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T215Y | Y188L | S68G, D121H, K122E, I135T, S162C, R172K, D177E, I178L, T200TA, E224D |
| >9115-30924| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLHEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFKKQNPELVIYQYMDDLLVGSDLEIGQHRAKIEELRQHLLRWGFYTP DKKHQKDPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, V82A, I84V | L33F, Q58E, T74P | L10V, I13V, K20R, M36I, N37D, R41RK, I62V, L63T, I64V, E65D |
| >9115-30924| codons 4-99 TLWQRPVVTVKIGGQLREALLDTGADDTVFEEIDLPGKWKPKIIGGIGGFIKVREYDQVT VDICGHKAIGPVLVGPTPANVIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |