Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9113 | 9113-30918 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184MV, T215F | K219Q | K103S, G190A | T39A, I94L, K122E, D123S, V179I, T200A, E203K, Q207E, K223Q, V245VM |
| >9113-30918| codons 38-247 CAEMEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGLPHP AGLKKSKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIIIYQYVDDLYVASDLEIGQHRAKIKELREHLLRWGFFTP DQKHQQEPPFLWMGYELHPDKWTVQPIMLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47V, V82C, L90M | L10F, F53FL, G73T | I62V, L63P, V77I, I93L |
| >9113-30918| codons 4-99 TLWQRPFVTIKIGGQLKEALLDTGADDTILEEMNLPGRWKPKIVGGIGGLIKVRQYDQVP IEICGHKAITTVLIGPTPCNIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |