<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9110 9110-30917 Brazil 2003 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, K70RT, L74V K219Q Y181C   V90VI, V118VI, K122E, I135T, I142IT, S162Y, K173T, Q174K, G196GR, T200A, I202IV, E203K, Q207E, R211A, F214L, D218E, L228HKNQ, V245Q N57NH, F61FS
>9110-30917| codons 38-247
CTEMEKEGKISKIGPENPYHTPVSAIKKKNSDTWRKVVDFRELNKRTQDFWEIQLGIPHP
AGLKKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGTRYQYNVLPQGWKGSP
AIFQYSMTKILEPFRTKNPDIVICQYMDDLYVGSDLEIRQHRAKVKELREHLLAWGLTTP
EQKHQKEPPFQWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54A, V82A   L10I, T12TN, I15V, K20R, E35D, M36I, N37NT, R41K, R57K, Q61N, I62V, L63C, A71V, T74S, L89LI, I93L  
>9110-30917| codons 4-99
TLWQRPIVNIKVGGQLREALLDTGADDTVLEDITLPGKWKPKMIGGIGGFAKVKQYDNVC
IEICGHKVIGSVLVGPTPANIIGRNILTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006