Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9110 | 9110-30917 | Brazil | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54A, V82A | L10I, T12TN, I15V, K20R, E35D, M36I, N37NT, R41K, R57K, Q61N, I62V, L63C, A71V, T74S, L89LI, I93L |
| >9110-30917| codons 4-99 TLWQRPIVNIKVGGQLREALLDTGADDTVLEDITLPGKWKPKMIGGIGGFAKVKQYDNVC IEICGHKVIGSVLVGPTPANIIGRNILTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, K70RT, L74V | K219Q | Y181C | V90VI, V118VI, K122E, I135T, I142IT, S162Y, K173T, Q174K, G196GR, T200A, I202IV, E203K, Q207E, R211A, F214L, D218E, L228HKNQ, V245Q | N57NH, F61FS |
| >9110-30917| codons 38-247 CTEMEKEGKISKIGPENPYHTPVSAIKKKNSDTWRKVVDFRELNKRTQDFWEIQLGIPHP AGLKKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGTRYQYNVLPQGWKGSP AIFQYSMTKILEPFRTKNPDIVICQYMDDLYVGSDLEIRQHRAKVKELREHLLAWGLTTP EQKHQKEPPFQWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |