Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9106 | 9106-30915 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A | L10FI, L24I, L33F | I15V, L19I, K43I, K55R, R57K, I62V, L63P, A71V |
| >9106-30915| codons 4-99 TLWQRPIVTIKVGGQIKEALIDTGADDTVFEEMNLPGRWIPKLIGGIGGFVRVKQYDQVP IEICGHKVIGTVLVGPTPANIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, V75M, M184MV, L210W, T215Y | F77L, K219N | K101KE, G190E | A98AG, E138K | T39A, E44ED, W88WS, I94IL, V118I, K122E, S162Y, V189VI, R211K, V245E |
| >9106-30915| codons 38-247 CAELEKDGKISKIGPENPYNTPVFAIKKKNSTKWRKLMDLRELNKRTQDFSEVQLGLPHP GGLEKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNKTPGIRYQYNVLPQGWKGSP AIFQYSMTKILEPFRKQNPDIVIYQYVDDLYIESDLEIGQHRTKIEELRQHLWKWGFYTP DNKHQKEPPFLWMGYELHPDKWTVQPIELP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |