<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9107 9107-30915 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I47IV, I54V, L76V, I84V, L90M V11I, G73GDNS, L89V L10I, I13V, I15V, K20V, M36MI, R57K, I62V, L63P, A71IV, T74S, T91TS, Q92K  
>9107-30915| codons 4-99
TLWQRPIITVKVGGQLVEALLDTGADDTVLEEINLPGRWKPKIVGGIGGFVKVKQYDQVP
IEICGHKVISSVVVGPTPVNVIGRNVMSKIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, M184V, L210W, T215Y D67G, K219R Y188L, G190A A98G K43KQ, E44D, K64R, D123E, I135T, I142V, S162C, D177E, V179I, I202T, H208Y, R211K, K223Q, L228H, V245E N57NH
>9107-30915| codons 38-247
CTELEQDGKISKIGPENPYHTPVFAIRKKGSTKWRKVVDFRELNKRTQDFWEVQLGIPHP
GGLKKKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSP
AIFQCSMTKILEPFRKQNPEIIIYQYVDDLLVASDLEIGQHRTKTEELRQYLWKWGFYTP
DRKHQQEPPFHWMGYELHPDKWTVQPIELP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006