Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9102 | 9102-30908 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | G73S | L10I, Q18H, L19P, K20I, L24F, L33V, M36I, N37S, I62V, L63P, A71T, I72R, I93M | H69L |
| >9102-30908| codons 4-99 TLWQRPIVTIKIGGHPIEALFDTGADDTVVEEISLPGRWKPKIIGGIGGFVKVRQYDQVP IEICGLKTRSTVLVGPTPVNVIGRNLMTQMGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, V75M, M184V, L210W, T215Y | F77L, K219N | T39A, E44D, V106I, V118VI, K122E, I135T, S162D, Q174R, D177E, I178L, V179VI, R211K, V245K |
| >9102-30908| codons 38-247 CAELEKDGKISKIGPENPYNTPVFAIKKKNSTKWRKLMDLRELNKRTQDFWEVQLGIPHP AGLKKKKSITVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQDSMTKILEPFRKRNPELIIYQYVDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTP DNKHQKEPPFLWMGYELHPDKWTVQPIKLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |