Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9380 | 9380-30930 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, L90M | L33F, G73S | L10I, I13IV, K14KR, I15V, L19V, K20KT, E35D, M36L, N37D, R57RK, I62V, L63P, A71V, I72L, I85IV |
| >9380-30930| codons 4-99 TLWQRPIVTVRVGGQVTEALLDTGADDTVFEDLDLPGRWKPKMIGGIGGFVKVKQYDQVP IEICGHKVLSTVLVGPTPANIVGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, K70R, T215F | K219Q | L100I, K103N | V118I, K122E, I135T, T139K, G196E, E203D, R211K, F214L, L228LH, H235HR, V245Q |
| >9380-30930| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHP AGIKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNEKPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRTKIDELRQHLLKWGLFTP DQKHQKEPPFHWMGYELRPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |