Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9379 | 9379-30930 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, L76V, I84V, L90M | V11I, G73S | L10I, K20I, E34Q, M36I, K55R, R57RK, I62V, L63P, H69R, A71V |
| >9379-30930| codons 4-99 TLWQRPIITIKIGGQLIEALLDTGADDTVLQEINLPGRWKPKIIGGIGGFVRVKQYDQVP IEICGRKVISTVVVGPTPVNVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, L74LI, T215F | K219Q | G190A | T39K, K43E, K101I, D123E, S162SDGN, K166R, D177E, V179I, G196E, L228LH |
| >9379-30930| codons 38-247 CKEMEEEGKISKIGPENPYNTPVFAIKKKNSTRWRKIVDFRELNKRTQDFWEVQLGIPHP AGLIKKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQNSMTRILEPFRKQNPEIIIYQYMDDLYVASDLEIEQHRTKIEELRQHLLRWGFFTP DQKHQKEPPFHWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |