Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9375 | 9375-30929 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V, V75T | L100I, K103N | D123E, I135T, V179VI, I202V, E203EQ, R211K, F214L, V245Q |
| >9375-30929| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKVTDFRELNKRTQDFWEVQLGIPHP AGIKKNKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIIIYQYMDDLYVGSDLEIGQHRTKVQELRQHLLKWGLTTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | L10V, I13V, Q18L, E35D, M36I, R41K, R57K, Q61N, I62V, T74S, V77I, L89M |
| >9375-30929| codons 4-99 TLWQRPVVTVKIGGLLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYDNVL IEICGHKAIGSVLIGPTPVNIIGRNMMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |