Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9160 | 9160-30924 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47V, I54V, L90M | L10F, Q58E, G73GS | I13V, K20I, M36I, N37S, I62V, L63P, A71T, I72IT, I93L |
| >9160-30924| codons 4-99 TLWQRPFVTVKIGGQLIEALLDTGADDTVLEEISLPGRWKPKIVGGIGGFVKVREYDQVP IEICGHKTTSTVLVGPTPVNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215F | L100I, K103N | T69TN, D121Y, K122E, D123E, I135T, I142V, S162A, I167IV, D177N, T200A, L228R, V245R |
| >9160-30924| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHP AGIKKNKSVTVLDVGDAYFSVPLYEEFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSP AIFQASMTKVLEPFRKQNPNIVIYQYVDDLYVGSDLEIGQHRAKIEELRQHLWRWGFFTP DKKHQKEPPFRWMGYELHPDKWTVQPIRLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |