Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9007 | 9007-30923 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L210W, T215Y | Y188L | V179D | V106I, K122E, D123E, I167V, K173T, T200A, R211K, E224D, D237A |
| >9007-30923| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSITVLDVGDAYFSVPLDEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKVLEPFRTQNPDIDIYQYMDDLLVGSDLEIGQHRAKIEELRQHLWKWGFYTP DKKHQKDPPFLWMGYELHPAKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I50V, V82M | L24I, L33F | L10I, T12P, K14R, E35ED, M36ML, K55R, L63P, C67DE, H69K, A71V, V77I |
| >9007-30923| codons 4-99 TLWQRPIVPIRIGGQLKEALIDTGADDTVFEDLNLPGRWKPKLIGGVGGFIRVRQYDQIP IEIEGKKVIGTVLIGPTPMNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |