Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9098 | 9098-30930 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, T215F | D67H, K219E | Y181C | T69N, A98S, K122KE, S162SN, K166KR, H208HY, R211K, D218E, L228H | K43HQ |
| >9098-30930| codons 38-247 CTEMEQEGKISKIGPENPYNTPVFAIKKKHSNRWRKLVDFRELNKRTQDFWEVQLGIPHP SGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQNSMTRILEPFRKQNPDIVICQYMDDLYVGSDLEIGQHRTKIEELRQYLLKWGFFTP EEKHQKEPPFHWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, L90M | L10F, F53FL | K20R, E35D, M36V, N37E, K55KR, R57K, D60E, I62V, L63P, A71V, V77I, I93L |
| >9098-30930| codons 4-99 TLWQRPFVTIKIGGQLREALLDTGADDTVLEDVELPGRWKPKMIGGIGGLVRVKQYEQVP IEICGHKVIGTVLIGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |