Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9097 | 9097-30930 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I50V, I54T, V82A | G73GA, L89V | L10I, I15V, K20R, E35D, M36I, R41K, I62V, L63P, G68GE, A71V, I72V, I85V |
| >9097-30930| codons 4-99 TLWQRPIVTIKVGGQLREALLDTGADDTVLEDINLPGKWKPKMIVGVGGFTKVRQYDQVP IEICEHKVVATVLVGPTPANIVGRNVLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74I, M184V, T215F | K219Q | K103N | K43Q, T69N, A98AS, D121H, K122E, I135T, S162C, K173Q, I178IL, T200A, D218E, L228H, V245E |
| >9097-30930| codons 38-247 CTELEQEGKISKIGPENPYNTPVFAIKKKNSNRWRKIVDFRELNKRTQDFWEVQLGIPHP SGLKKNKSVTVLDVGDAYFSVPLHEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRQQNPDLVIYQYVDDLYVGSDLEIGQHRAKIEELRQHLLRWGFFTP EQKHQKEPPFHWMGYELHPDKWTVQPIELP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |