Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9095 | 9095-30925 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, M184V, L210W, T215Y | K219R | K103N, Y181C, G190A | V108I | K43E, E44A, K49R, E53D, V118I, K122E, S162D, R172K, G196Q, E203ED, H208Y, R211K, H221Y, L228Q | Q182H |
| >9095-30925| codons 38-247 CTELEEAGKISRIGPDNPYNTPVFAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQDSMTKILEPFKKQNPDIVICHYVDDLYVASDLEIQQHRTKIDELRQYLWKWGFYTP DRKYQKEPPFQWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I50V, I54V, L76V, V82A | L33F, Q58QE, L89MV | L10I, I13V, K20R, E35D, M36I, N37E, K55R, R57K, D60E, I62V, L63P, I66F, K70R, A71AV, V77VI |
| >9095-30925| codons 4-99 TLWQRPIVTVKIGGQLREALLDTGADDTVFEDIELPGRWKPKIIGGVGGFVRVKEYEQVP IEFCGHRVIGTVVIGPTPANIIGRNVLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |