<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9095 9095-30925 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I50V, I54V, L76V, V82A L33F, Q58QE, L89MV L10I, I13V, K20R, E35D, M36I, N37E, K55R, R57K, D60E, I62V, L63P, I66F, K70R, A71AV, V77VI  
>9095-30925| codons 4-99
TLWQRPIVTVKIGGQLREALLDTGADDTVFEDIELPGRWKPKIIGGVGGFVRVKEYEQVP
IEFCGHRVIGTVVIGPTPANIIGRNVLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, L210W, T215Y K219R K103N, Y181C, G190A V108I K43E, E44A, K49R, E53D, V118I, K122E, S162D, R172K, G196Q, E203ED, H208Y, R211K, H221Y, L228Q Q182H
>9095-30925| codons 38-247
CTELEEAGKISRIGPDNPYNTPVFAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP
AGLKKNKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQDSMTKILEPFKKQNPDIVICHYVDDLYVASDLEIQQHRTKIDELRQYLWKWGFYTP
DRKYQKEPPFQWMGYELHPDKWTVQPIVLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006