Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9093 | 9093-30827 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, L76LV, V82A | L10I, I15V, G16E, K20KT, R41K, L63H, A71T |
| >9093-30827| codons 4-99 TLWQRPIVTIKVEGQLTEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFVKVRQYDQIH IEICGHKTIGTVVVGPTPANIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151QKLM, M184V | F116Y | K103DN | E42G, K102R, V111M, K122E, I135IT, I178M, I202V | T84TP |
| >9093-30827| codons 38-247 CTEMGKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRPQDFWEVQLGIPHP AGLKRNKSVTVLDMGDAYYSVPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSP AIFQSSMTKILEPFRKQNPDMVIYQYVDDLYVGSDLEIGQHRTKVEELRQHLLRWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |